Noltrex

What is Noltrex®Vet?

Noltrex®Vet is a synthetic hydrogel comprised primarily of 3-dimensional polyacrylamide (4%) with a high molecular weight of 10 million daltons. To put that into context, Noltrex®Vet has a molecular weight 3-5 times greater than high molecular weight hyaluronic acids or HA (a large component of normal joint fluid).

A higher molecular weight molecule will take longer to break down in the joint of the horse, therefore maintaining effectiveness for longer than a product with a lower molecular weight. Thus, Noltrex®Vet has a substantial advantage over previous equine joint therapies.

Noltrex®Vet substitutes for the lack of lubricating properties of compromised joint fluid to reduce friction and provide physical protection to the cartilage. Protecting sensitive cartilage is critical in order to maintain healthy and pain-free joints in horses.

Noltrex®Vet was recommended for high-motion joints.

Common examples would include coffin joints, fetlocks and stifles. However, other joints considered low motion joints (limited movement, but important) have also shown great improvement from Noltrex®Vet therapy. The most common example of a low motion joint would be lower hock joints.

How long does it take to see improvements with Noltrex®Vet?

Response to treatment with Noltrex®Vet will vary between horses. Some horses show improvement within days after injection, while others may take up to 30 days.

Generally, gradual improvement is seen over a 1-3 week period. If a horse makes improvement from a single injection, but is not 100%, then a second injection after 5-6 weeks should be considered.